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Myopia research / Evidence explorer

Explore the BLINK study

Compare the adjusted three-year outcomes from the 2020 BLINK trial. Switch outcomes to see why the measure matters.

BLINK · Randomized clinical trial

Three years, compared.

Adjusted change in refraction (diopters). More negative values mean greater myopia progression.

Single visionControl
-1.05 D
Medium add+1.50 D
-0.89 D
High add+2.50 D
-0.60 D
High add vs. single vision0.46 D less progression

Published adjusted difference; 95% CI 0.29 to 0.63 D.

Contrasts use the study's statistical model. They may differ from subtraction of rounded chart values.

View the numbers and study context
Adjusted three-year group means
Lens groupRefraction changeAxial growth
Single vision-1.05 D0.66 mm
Medium add-0.89 D0.58 mm
High add-0.60 D0.42 mm

294 children, aged 7-11 at enrollment; three years of follow-up. The primary outcome was myopia progression. Axial elongation was a secondary outcome. The chart shows endpoint means, not individual trajectories or confidence intervals. Medium-add vs. single-vision progression did not reach statistical significance (95% CI −0.01 to 0.33 D).

The idea to take away

High-add lenses slowed progression compared with single-vision lenses in this trial. Slower progression is not a reversal of myopia.

What this study can tell us

This trial enrolled 294 children aged 7-11 at two US centers. The results apply to the studied lenses, population, and follow-up period. Group averages do not predict an individual child's outcome or compare all myopia treatments.

Check your understanding

What can we conclude from the high-add group?

Teach this research

Inspect a short presentation built from this study, including its question, evidence, and production notes.

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References checked October 1, 2026
Primary research

The BLINK randomized clinical trial

Walline et al. · JAMA · 2020

Three-year comparison of high-add, medium-add, and single-vision contact lenses. DOI: 10.1001/jama.2020.10834.

Research summary

Multifocal contact lenses slow myopia progression in children

National Eye Institute · 2020

An accessible introduction to the trial and its findings.

Up next: The myopia optics lab